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Cpic guidelines are designed to help clinicians understand how available genetic test results should be used to optimize drug therapy, rather than whether tests should be ordered. This guideline updates and expands the 2015 clinical pharmacogenetics implementation consortium (cpic) guideline for cyp2d6 and cyp2c19 genotypes and ssri dosing and summarizes the impact of cyp2d6, cyp2c19, cyp2b6, slc6a4, and htr2a genotypes on antidepressant dosing, efficacy, and tolerability. The clinical pharmacogenetics implementation consortium (cpic®) is an international consortium interested in facilitating the use of pharmacogenetic tests for patient care Caudle presents on cpic’s newest findings and current guidelines.
Clinical pharmacogenetics implementation consortium (cpic) guideline for cyp2d6, cyp2c19, cyp2b6, slc6a4, and htr2a genotypes and serotonin reuptake inhibitor antidepressants (april 2023) Selective serotonin reuptake inhibitors (ssris) are primary treatment options for major depressive and anxiety disorders Cyp2d6 and cyp2c19 polymorphisms can influence the metabolism of ssris, thereby affecting drug efficacy and safety. Contact us now to get started.
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