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In this review, we discuss the molecular landscape of um, including canonical genetic, transcriptomic and tumour microenvironment (tme) features B cells were recruited to the tumor microenvironment after 3 doses of tebentafusp, with evidence of new tertiary lymphoid structures These limitations, alongside the retrospective nature of the study and the difference in baseline characteristics, favoring group 2 (ici first), suggest that although tebentafusp after treatment with icis might enhance antitumor activity, this observation merits further investigation in prospective clinical trials. Tebentafusp (tebe) (gp100×cd3) is the first tcr bispecific protein approved for treatment of a solid tumor (metastatic uveal melanoma, mum)
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