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(see diagnosis of acute myocardial infarction, section on 'definitions'.) however, troponin is not specific for acute thrombotic occlusion of a coronary artery, the most common precursor to acute myocardial infarction. Ekg is a good initial test for ischemia because minor, nonspecific abnormalities won't trigger a huge ischemia evaluation. Troponin can be temporally elevated in some situations, a finding that is related to increased membrane permeability
53 the myocardial depressing factors released in sepsis and other inflammatory conditions cause troponin to be fragmented into low molecular weight particles in situ. Troponin should only be obtained if there is genuine concern for myocardial ischemia based on history and ekg The term troponin leak is often used informally to describe elevated troponin levels when the cause is not a classic heart attack
The more precise clinical term for this finding is myocardial injury, which is defined as an elevated cardiac troponin value above the 99th percentile of the upper reference limit.
What is a troponin test A troponin test looks for the protein troponin (there are two forms related to your heart, troponin i and troponin t) in your blood Normally, troponin stays inside your heart muscle's cells, but damage to those cells — like the kind of damage from a heart attack — causes troponin to leak into your blood Higher levels of troponin in your blood also mean more.
Cardiac troponin (ctn) testing is an essential component of the diagnostic workup and management of acute coronary syndromes (acs) Cardiac troponin is a preferred biomarker of acute myocardial infarction (mi) Unfortunately, elevation of troponin can be detected in a variety of conditions other than acute mi This review focuses on the incidence and clinical significance of increased troponin in conditions commonly associated with troponin elevations, particularly in those that may resemble acute mi.
Differential diagnosis unstable angina myocardial injury/ troponin leak tachyarrhythmia, severe hypertension, marathon running, stimulant use, chf exacerbation, hypotension, lack of clearance from renal failure, other
Troponin levels are measured with a blood test, and high levels may be a sign of heart damage.
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